C. Tanner et al, Volume and Shape Preservation of Enhancing Lesions when applying Non
-Rigid Registration to a Time Series of Contrast Enhancing MR Breast
Images, MICCAI00
In this paper we show first that a non-rigid registration algorithm
used to register time-series MR images of the breast,
can result in significant
volume changes in the region of the enhanced lesion. Since this is
physically implausible, given the short duration of the MR time series
acquisition, the non-rigid registration algorithm was extended to allow the
incorporation of rigid regions. In this way the registration is done in two
stages. The enhanced lesions are first detected using the non-rigid
registration algorithm in its original form. Secondly, the region of the
enhanced lesion is set to be rigid and the new algorithm is applied to
integrate this rigid region into the existing registration. By definition,
volume and shape will be preserved in this rigid region. Preliminary results of
applying this algorithm to 15 datasets are described.
Last modified: Tue Jan 29 17:15:50 GMT 2002